![]() ![]() There’s been a growing consensus that SARS-CoV-2 affects the vascular system, but exactly how it did so was not understood. While the findings themselves aren’t entirely a surprise, the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time. Salk researchers collaborated with scientists at the University of California San Diego on the paper, including co-first author Jiao Zhang and co-senior author John Shyy, among others. The commonality between them is that they all have vascular underpinnings.” “That could explain why some people have strokes, and why some people have issues in other parts of the body. “A lot of people think of it as a respiratory disease, but it’s really a vascular disease,” says Assistant Research Professor Uri Manor, who is co-senior author of the study. Representative images of vascular endothelial control cells (left) and cells treated with the SARS-CoV-2 Spike protein (right) show that the spike protein causes increased mitochondrial fragmentation in vascular cells. The findings help explain COVID-19’s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies. The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. Now, a major new study shows that the virus spike proteins (which behave very differently than those safely encoded by vaccines) also play a key role in the disease itself. LA JOLLA-Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease April 30, 2021 And in the meantime, of course, keep wearing your mask and staying socially distanced when appropriate.ApThe novel coronavirus’ spike protein plays additional key role in illness ![]() If you're not sure where to get one near you, check out the new site, which will point you in the direction of a vaccination site. now and all adults in the country eligible to get one, it's easier than ever to take this crucial step to help protect yourself and those around you. With three COVID-19 vaccines authorized for use in the U.S. Still, it's better for them to actually get vaccinated, she explained. “Wrong reasons, right answer,” Angela Rasmussen, Ph.D., a virologist at the University of Saskatchewan Vaccine and Infectious Disease Organization, said on Twitter. If COVID-19 conspiracy theories like these get otherwise skeptical people on board with those public health measures, that could be a bit of a win. “If you are trying to become pregnant, you do not need to avoid pregnancy after receiving a COVID-19 vaccine.”īut, as most of us know by now, wearing a face mask and staying at least six feet away from others are two crucial ways to reduce the spread of COVID-19 and limit the toll of the coronavirus pandemic. “There is currently no evidence that any vaccines, including COVID-19 vaccines, cause fertility problems,” the CDC says. You also don't need to be worried that getting the vaccine might affect your fertility or your ability to conceive in the future, the Centers for Disease Control and Prevention (CDC) say. Other smaller studies have seen similar results, suggesting that pregnant people are not at an increased risk for major side effects from the vaccine or other effects, like a miscarriage. For instance, a large study published in the New England Journal of Medicine earlier this year found that rates of pregnancy loss and preterm birth among nearly 35,700 pregnant people who received a COVID-19 vaccine were similar to the average rates of those events in other studies before the pandemic. And the claims that the COVID-19 vaccine can cause miscarriages or negatively affect fertility are also baseless. ![]()
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